Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 6/20 | 0.58 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.58 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.48 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.48 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 4/20 | 0.45 |
| ▸ | TEK | Q02763 | 4/20 | 0.45 |
| ▸ | ERN1 | O75460 | 1/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5935193 | 0.89 | CYP11B1 (0.63) | CYP11B1CYP11B2IDO1 | |
| SCHEMBL8133106 | 0.83 | CYP11B1 (0.63) | CYP11B1CYP11B2CYP2A6SMN1; SMN2IDO1 | |
| SCHEMBL7983220 | 0.82 | CYP11B1 (0.62) | CYP11B1CYP11B2SMN1; SMN2IDO1ALDH1A1 | |
| SCHEMBL8138162 | 0.81 | CYP11B1 (0.55) | CYP11B1CYP11B2GRM2IDO1CYP3A4 | |
| SCHEMBL1757759 | 0.79 | CYP11B1 (0.66) | CYP11B1CYP11B2IDO1ALDH1A1 | |
| SCHEMBL7696643 | 0.79 | CYP11B1 (0.66) | CYP11B1CYP11B2IDO1ALDH1A1 | |
| SCHEMBL8135755 | 0.79 | CYP11B1 (0.65) | CYP11B1CYP11B2IDO1ALDH1A1 | |
| SCHEMBL8131698 | 0.78 | CYP11B1 (0.58) | CYP11B1CYP11B2CYP2A6GRM2IDO1 | |
| SCHEMBL14476244 | 0.78 | CYP11B1 (0.58) | CYP11B1CYP11B2MKNK1MKNK2TEK | |
| SCHEMBL1758083 | 0.78 | CYP11B1 (0.68) | CYP11B1CYP11B2CYP2A6SMN1; SMN2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001009124-A1 | 8-CARBONYL CHROMAN DERIVATIVES, PREPARATION AND THERAPIC USE THEREOF | AVENTIS PHARMA S.A. (FR) | 2001-02-08 | — | — | WO | disclosed |