Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 6/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CASP7 | P55210 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14141546 | 0.85 | ADRB2 (0.54) | ADRB2HIF1ATSHRADRB1CYP1A2 | |
| SCHEMBL12158793 | 0.83 | ADRB2 (0.66) | ADRB2HIF1ATSHRADRB1CYP1A2 | |
| SCHEMBL6838978 | 0.83 | ADRB2 (0.66) | ADRB2HIF1ATSHRADRB1CYP1A2 | |
| Albuterol SCHEMBL7973408 | 0.83 | ADRB2 (0.70) | ADRB2HIF1ATSHRADRB1CYP1A2 | |
| SCHEMBL14141543 | 0.82 | ADRB2 (0.62) | ADRB2HIF1ATSHRADRB1CYP1A2 | |
| Albuterol SCHEMBL3133773 | 0.80 | PMP22 (0.74) | ADRB2HIF1ATSHRADRB1CYP1A2 | |
| SCHEMBL11289635 | 0.78 | ADRB2 (0.59) | ADRB2HIF1ATSHRADRB1CYP1A2 | |
| SCHEMBL28915488 | 0.78 | ADRB2 (0.69) | ADRB2HIF1ATSHRADRB1CYP1A2 | |
| SCHEMBL6700369 | 0.78 | ADRB2 (0.72) | ADRB2HIF1ATSHRADRB1CYP1A2 | |
| SCHEMBL7778381 | 0.76 | ADRB2 (0.56) | ADRB2HIF1ATSHRADRB1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1069887-A1 | AEROSOL COMPOSITION | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LTD. (GB) | 2001-01-24 | — | — | EP | disclosed |
| WO-1999051205-A1 | AEROSOL COMPOSITION | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 1999-10-14 | — | — | WO | disclosed |