Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 9/20 | 0.59 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.49 |
| ▸ | CASP7 | P55210 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12158793 | 0.85 | ADRB2 (0.66) | ADRB2ADRB1HIF1ATSHRCYP1A2 | |
| SCHEMBL6838978 | 0.85 | ADRB2 (0.66) | ADRB2ADRB1HIF1ATSHRCYP1A2 | |
| SCHEMBL11281997 | 0.84 | HIF1A (0.51) | ADRB2ADRB1HIF1ATSHRCYP1A2 | |
| SCHEMBL11290216 | 0.83 | PMP22 (0.48) | ADRB2ADRB1HIF1ATSHRCYP1A2 | |
| SCHEMBL11289637 | 0.83 | ADRB2 (0.63) | ADRB2ADRB1HIF1ATSHRCYP1A2 | |
| SCHEMBL14141543 | 0.82 | ADRB2 (0.62) | ADRB2ADRB1HIF1ATSHRCYP1A2 | |
| SCHEMBL6700369 | 0.80 | ADRB2 (0.72) | ADRB2ADRB1HIF1ATSHRCYP1A2 | |
| SCHEMBL4632760 | 0.79 | ADRB2 (0.52) | ADRB2ADRB1HIF1ATSHRCYP1A2 | |
| SCHEMBL11283530 | 0.78 | ADRB2 (0.52) | ADRB2ADRB1HIF1ATSHRCYP1A2 | |
| SCHEMBL7973412 | 0.78 | ADRB2 (0.57) | ADRB2ADRB1HIF1ATSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-RE30241-E | BRONCHODILATION, ADRENERGIC STIMULANTS | STERLING DRUG INC. (US) | 1980-03-25 | — | — | US | disclosed |
| US-4138581-A | BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS | STERLING DRUGS INC. (US) | 1979-02-06 | — | — | US | disclosed |