Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7973333 | 0.94 | TSHR (0.33) | TSHRLMNAHCAR2FAAH | |
| SCHEMBL9620463 | 0.88 | LMNA (0.39) | TSHRLMNAHCAR2FAAH | |
| SCHEMBL7066356 | 0.88 | TSHR (0.37) | TSHRLMNAHCAR2 | |
| SCHEMBL8784853 | 0.85 | TSHR (0.42) | TSHRLMNAHCAR2 | |
| SCHEMBL7976135 | 0.79 | CA1 (0.39) | TSHR | |
| SCHEMBL21811446 | 0.79 | LMNA (0.39) | TSHRLMNAHCAR2FAAH | |
| SCHEMBL8924479 | 0.79 | TSHR (0.40) | TSHRLMNAHCAR2 | |
| SCHEMBL7971410 | 0.78 | SMN1; SMN2 (0.41) | TSHRLMNAHCAR2 | |
| SCHEMBL21811500 | 0.74 | TSHR (0.40) | TSHRLMNAHCAR2 | |
| SCHEMBL7970891 | 0.73 | ZDHHC7 (0.40) | TSHRLMNAFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172234-B1 | Optically active cyclic amino acid ester derivatives and processes for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-0976729-A1 | Optically active cyclic amino acid ester derivatives and processes for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-02-02 | — | — | EP | disclosed |