Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8784853 | 0.89 | TSHR (0.42) | TSHRLMNASMN1; SMN2HCAR2 | |
| SCHEMBL7973414 | 0.88 | TSHR (0.34) | TSHRLMNAHCAR2 | |
| SCHEMBL7973333 | 0.86 | TSHR (0.33) | TSHRLMNAHCAR2 | |
| SCHEMBL9620463 | 0.83 | LMNA (0.39) | TSHRLMNASMN1; SMN2HCAR2 | |
| SCHEMBL21811446 | 0.83 | LMNA (0.39) | TSHRLMNASMN1; SMN2HCAR2 | |
| SCHEMBL8924479 | 0.82 | TSHR (0.40) | TSHRLMNAHCAR2 | |
| SCHEMBL28124632 | 0.81 | TSHR (0.36) | TSHRLMNASMN1; SMN2 | |
| SCHEMBL9065152 | 0.80 | TSHR (0.39) | TSHRLMNAHCAR2 | |
| SCHEMBL28232550 | 0.79 | LMNA (0.46) | TSHRLMNA | |
| SCHEMBL28407846 | 0.78 | TSHR (0.37) | TSHRLMNAHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0827954-B1 | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL CO (JP) | 2003-06-04 | — | — | EP | disclosed |
| US-6114543-A | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| US-5880291-A | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-03-09 | — | — | US | disclosed |
| EP-0827954-A1 | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1998-03-11 | — | — | EP | disclosed |