Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 8/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971486 | 0.88 | LMNA (0.56) | OPRM1OPRD1OPRK1LMNAGRIN2D | |
| SCHEMBL20482160 | 0.86 | PDE4B (0.57) | PDE4BOPRM1OPRD1OPRK1LMNA | |
| SCHEMBL3691973 | 0.85 | OPRM1 (0.61) | OPRM1OPRD1OPRK1GRIN2DGRIN3B | |
| SCHEMBL5831347 | 0.85 | LMNA (0.55) | LMNAMAPTTSHRCYP1A2CYP3A4 | |
| SCHEMBL20482499 | 0.83 | PDE4B (0.54) | PDE4BOPRM1OPRD1OPRK1LMNA | |
| SCHEMBL19362909 | 0.83 | PDE4B (0.54) | PDE4BLMNAMAPTTSHRNPSR1 | |
| SCHEMBL19362950 | 0.82 | PDE4B (0.58) | PDE4BLMNAMAPTTSHRKMT2A | |
| SCHEMBL6179875 | 0.81 | PDE4B (0.57) | PDE4BOPRM1OPRD1OPRK1LMNA | |
| SCHEMBL21656688 | 0.81 | PDE4B (0.53) | PDE4BOPRM1OPRD1OPRK1LMNA | |
| SCHEMBL19363006 | 0.81 | PDE4B (0.53) | PDE4BLMNAMAPTTSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001036412-A1 | PROCESS FOR THE PREPARATION OF ARYLOXY PROPANOLAMINES | ELI LILLY AND COMPANY (US) | 2001-05-25 | — | — | WO | disclosed |