Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 7/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4575843 | 1.00 | OPRD1 (0.35) | OPRD1OPRM1CYP1A2CYP3A4 | |
| SCHEMBL6939887 | 1.00 | OPRD1 (0.35) | OPRD1OPRM1CYP1A2CYP3A4 | |
| SCHEMBL6939883 | 1.00 | OPRD1 (0.35) | OPRD1OPRM1CYP1A2CYP3A4 | |
| SCHEMBL6939892 | 1.00 | OPRD1 (0.35) | OPRD1OPRM1CYP1A2CYP3A4 | |
| SCHEMBL6928895 | 0.89 | OPRD1 (0.33) | OPRD1OPRM1CYP1A2CYP3A4 | |
| SCHEMBL2751545 | 0.88 | OPRD1 (0.43) | OPRD1OPRM1 | |
| SCHEMBL6935964 | 0.85 | OPRD1 (0.35) | OPRD1OPRM1CYP1A2CYP3A4 | |
| SCHEMBL6935966 | 0.85 | OPRD1 (0.35) | OPRD1OPRM1CYP1A2CYP3A4 | |
| SCHEMBL6935960 | 0.83 | OPRD1 (0.56) | OPRD1OPRM1CYP1A2CYP3A4 | |
| SCHEMBL7971321 | 0.79 | OPRD1 (0.50) | OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6200978-B1 | FOR PREVENTING OR TREATING INFLAMMATORY DISEASES SUCH AS ARTHRITIS, PSORIASIS, ASTHMA, OR INFLAMMATORY BOWEL DISEASE, DISORDERS OF RESPIRATORY FUNCTION, GASTROINTESTINAL DISORDERS SUCH AS FUNCTIONAL BOWEL DISEASE, AS ANALGESICS | PFIZER INC. | 2001-03-13 | — | — | US | disclosed |