Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | PKLR | P30613 | 1/20 | 0.59 |
| ▸ | GABRP | O00591 | 3/20 | 0.51 |
| ▸ | GABRD | O14764 | 3/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.51 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.51 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.51 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.51 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.51 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.51 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.51 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.51 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.51 |
| ▸ | GABRE | P78334 | 3/20 | 0.51 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.51 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.51 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.51 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.51 |
| ▸ | PTPRA | P18433 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8629832 | 0.88 | NQO2 (0.67) | NQO2PKMPKLRPTPRAMAPT | |
| SCHEMBL31098035 | 0.88 | NQO2 (0.67) | NQO2PKMPKLRPTPRAMAPT | |
| SCHEMBL27929617 | 0.87 | NQO2 (0.61) | NQO2PKMPKLRGABRPGABRD | |
| SCHEMBL3294986 | 0.86 | NQO2 (0.64) | NQO2PKMPKLRMAPTSMN1; SMN2 | |
| SCHEMBL4351496 | 0.85 | NQO2 (0.64) | NQO2PKMPKLRPTPRAMAPT | |
| SCHEMBL947883 | 0.84 | NQO2 (0.59) | NQO2PKMPKLRGABRPGABRD | |
| SCHEMBL7008593 | 0.84 | NQO2 (0.66) | NQO2PKMPKLRMAPTSMN1; SMN2 | |
| SCHEMBL9664626 | 0.84 | NQO2 (0.59) | NQO2PKMPKLRGABRPGABRD | |
| SCHEMBL18189675 | 0.84 | TSHR (0.62) | NQO2PKMPKLRGABRPGABRD | |
| SCHEMBL31573286 | 0.82 | LTA4H (0.65) | NQO2PKMPKLRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105030766-A | Indole-3-carbinol, di-indolyl methane and application of derivatives of indole-3-carbinol and di-indolyl methane to medicine for treating allergic pharyngitis | ANHUI SIZHENG MEDICAL TECHNOLOGY CO LTD | 2015-11-11 | — | — | CN | disclosed |
| CN-105012297-A | Use of indole-3-carbinol, bis-indolymethane and derivatives thereof in drugs for treatment on contact dermatitis | ANHUI SIZHENG MEDICAL TECHNOLOGY CO LTD | 2015-11-04 | — | — | CN | disclosed |
| CN-104997772-A | Application of indole-3-methanol, diindolylmethane and derivatives thereof in drugs used for treating psoriasis | ANHUI SIZHENG MEDICAL TECHNOLOGY CO LTD | 2015-10-28 | — | — | CN | disclosed |
| CN-104940194-A | Application of benzpyrole-3-methyl alcohol, diindolylmethane and ramification thereof used for medicine for treating refractory periodontitis | ANHUI SIZHENG MEDICAL TECHNOLOGY CO LTD | 2015-09-30 | — | — | CN | disclosed |
| CN-104922112-A | Indole-3-carbinol, diindolylmethane and application of derivatives of indole-3-carbinol and diindolylmethane to medicines for treatment of prostatitis | ANHUI SIZHENG MEDICAL TECHNOLOGY CO LTD | 2015-09-23 | — | — | CN | disclosed |
| CN-104922114-A | Indole-3-carbinol, diindolylmethane and application of derivatives of indole-3-carbinol and diindolylmethane to medicines for treatment of chronic esophagitis | ANHUI SIZHENG MEDICAL TECHNOLOGY CO LTD | 2015-09-23 | — | — | CN | disclosed |
| CN-104922113-A | Indole-3-carbinol, diindolylmethane and application of derivatives of indole-3-carbinol and diindolylmethane to medicines for treatment of gastric ulcer | ANHUI SIZHENG MEDICAL TECHNOLOGY CO LTD | 2015-09-23 | — | — | CN | disclosed |
| CN-104906086-A | Application of indole-3-methaol, bis(indoly)methane and derivatives thereof in medicine for treating glomerulonephritis | ANHUI SIZHENG PHARMACEUTICAL TECHNOLOGY CO LTD | 2015-09-16 | — | — | CN | disclosed |
| CN-102335168-B | Application of indole-3-carbinol, diindolyl methane and derivatives thereof in preparation of medicaments for treating osteoporosis | BOLTEC BIOPHARM CO LTD | 2014-04-02 | — | — | CN | disclosed |
| CN-102335169-B | Application of indole-3-carbinol, diindolyl methane and derivatives thereof in preparation of medicaments for treating senile dementia | HEFEI BOTAI MEDICAL BIO TECHNOLOGY DEV CO LTD | 2014-03-19 | — | — | CN | disclosed |
| CN-101940568-B | Application of indole-3-methanol, diindolylmethane and derivatives thereof in preparing medicament for treating cardiac failure caused by anthracycline | BOTAI BIO PHARM TECHNOLOGY CO LTD | 2012-11-14 | — | — | CN | disclosed |
| CN-102429901-A | Application of indole-3-methanol, diindolylmethane and derivatives thereof in preparation of medicines for preventing and treating renal fibrosis | HEFEI BOLTEC BIOPHARM TECHNOLOGY DEV CO LTD | 2012-05-02 | — | — | CN | disclosed |
| CN-102389419-A | Application of indole-3-carbinol, diindolylmethane and derivatives thereof to preparation of medicine for preventing and controlling atherosclerosis | HEFEI BOTAI MEDICAL BIO TECHNOLOGY DEV CO LTD | 2012-03-28 | — | — | CN | disclosed |
| CN-102389420-A | Applications of indole-3-carbinol, diindolylmethane and derivatives thereof in preparation of medicaments for preventing and treating pulmonary fibrosis | HEFEI BOTAI MEDICAL BIO TECHNOLOGY DEV CO LTD | 2012-03-28 | — | — | CN | disclosed |
| WO-2012037034-A1 | E-SELECTIN ANTAGONISTS | GLYCOMIMETICS, INC. (US) | 2012-03-22 | — | — | WO | disclosed |
| CN-102335169-A | Application of indole-3-carbinol, diindolyl methane and derivatives thereof in preparation of medicaments for treating senile dementia | HEFEI BOTAI MEDICAL BIO TECHNOLOGY DEV CO LTD | 2012-02-01 | — | — | CN | disclosed |
| CN-102335168-A | Application of indole-3-carbinol, diindolyl methane and derivatives thereof in preparation of medicaments for treating osteoporosis | HEFEI BOTAI MEDICAL BIO TECHNOLOGY DEV CO LTD | 2012-02-01 | — | — | CN | disclosed |
| CN-102327262-A | Indole-3-methanol, diindolylmethane and application of derivative thereof in preparation of drug for treating diabetes | HEFEI BOLTEC BIOPHARM CO LTD | 2012-01-25 | — | — | CN | disclosed |
| CN-101940568-A | Application of indole-3-methanol, diindolylmethane and derivatives thereof in preparing medicament for treating cardiac failure caused by anthracycline | BOTAI BIO PHARM TECHNOLOGY CO LTD | 2011-01-12 | — | — | CN | disclosed |
| US-20090239760-A1 | Method for the Identification of New Leads for Drug Candidates | UNIVERSITY OF BASEL (CH) | 2009-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090239760-A1 | Method for the Identification of New Leads for Drug Candidates | MAG, PMP22, MAGI3 | NQO2 1416/4885PKM 3232/4885PKLR 3445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.