Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | PKLR | P30613 | 1/20 | 0.56 |
| ▸ | MPO | P05164 | 1/20 | 0.55 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | PTPRA | P18433 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CLK1 | P49759 | 1/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.46 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | GABRP | O00591 | 1/20 | 0.45 |
| ▸ | GABRD | O14764 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1520627 | 0.88 | LTA4H (0.65) | NQO2PKMPKLRMPOLTA4H | |
| SCHEMBL31573286 | 0.88 | LTA4H (0.65) | NQO2PKMPKLRMPOLTA4H | |
| SCHEMBL27929617 | 0.87 | NQO2 (0.61) | NQO2PKMPKLRLTA4HPLA2G2A | |
| Hydrochloric Acid SCHEMBL21546050 | 0.87 | LTA4H (0.67) | NQO2PKMPKLRMPOLTA4H | |
| SCHEMBL3294986 | 0.86 | NQO2 (0.64) | NQO2PKMPKLRMAPTSMN1; SMN2 | |
| SCHEMBL947883 | 0.84 | NQO2 (0.59) | NQO2PKMPKLRLTA4HPLA2G2A | |
| SCHEMBL7008593 | 0.84 | NQO2 (0.66) | NQO2PKMPKLRMPOLTA4H | |
| SCHEMBL797369 | 0.84 | NQO2 (0.62) | NQO2PKMPKLRPTPRACYP2C19 | |
| SCHEMBL11537110 | 0.82 | NQO2 (0.63) | NQO2PKMPKLRLTA4HPLA2G2A | |
| SCHEMBL8629832 | 0.82 | NQO2 (0.67) | NQO2PKMPKLRLTA4HPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240352-B1 | 5-FLUOROURACIL DERIVATIVES AND PROCESSES FOR PRODUCING THEREOF | Chisso Corporation (JP) | 1992-12-16 | — | — | EP | disclosed |
| US-4792607-A | ANTICANCER MEDICINE INTERRMEDIATES | CHISSO CORPORATION (JP) | 1988-12-20 | — | — | US | disclosed |
| EP-0240352-A2 | 5-Fluorouracil derivatives and processes for producing thereof | Chisso Corporation (JP) | 1987-10-07 | — | — | EP | disclosed |