Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 10/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 8/20 | 0.39 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1267155 | 0.85 | TSHR (0.38) | TSHRCHRM2CHRM3CHRM1CHRM4 | |
| SCHEMBL1267152 | 0.85 | TSHR (0.38) | TSHRCHRM2CHRM3CHRM1CHRM4 | |
| SCHEMBL17158486 | 0.85 | GSTO1 (0.37) | CHRM2CHRM3CHRM5 | |
| SCHEMBL17815875 | 0.81 | MEN1 (0.42) | TSHRCHRM2CHRM3CHRM1CHRM4 | |
| SCHEMBL5208182 | 0.81 | MEN1 (0.42) | TSHRCHRM2CHRM3CHRM1CHRM4 | |
| SCHEMBL13275669 | 0.76 | L3MBTL1 (0.44) | TSHRCHRM2CHRM3CHRM1CHRM4 | |
| SCHEMBL20925575 | 0.76 | L3MBTL1 (0.44) | TSHRCHRM2CHRM3CHRM1CHRM4 | |
| SCHEMBL15615606 | 0.76 | L3MBTL1 (0.44) | TSHRCHRM2CHRM3CHRM1CHRM4 | |
| SCHEMBL16934616 | 0.76 | L3MBTL1 (0.44) | TSHRCHRM2CHRM3CHRM1CHRM4 | |
| SCHEMBL31586083 | 0.75 | HCRTR2 (0.40) | KDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207668-B1 | FOR CONTROLLING INSECTS OR THEIR EGGS; AS FUNGICIDES, OVICIDES OR AS VETERINARY MEDICAMENTS | HOECHST SCHERING (DE) | 2001-03-27 | — | — | US | disclosed |
| EP-0892798-A1 | SUBSTITUTED PYRIDINES/PYRIMIDINES, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF AS PESTICIDES | Hoechst Schering AgrEvo GmbH (DE) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997037991-A1 | SUBSTITUTED PYRIDINES/PYRIMIDINES, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF AS PESTICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1997-10-16 | — | — | WO | disclosed |