SCHEMBL7973704

SCHEMBL7973704

NC(Cc1ccc2c(c1)C(=O)c1ccccc1-2)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 4/20 0.59
PTGS1 P23219 2/20 0.59
PKM P14618 2/20 0.59
ALPI P09923 1/20 0.59
XIAP P98170 1/20 0.59
SLC1A3 P43003 1/20 0.57
SLC1A2 P43004 1/20 0.57
SLC1A1 P43005 1/20 0.57
KDM4E B2RXH2 1/20 0.55
USP2 O75604 1/20 0.55
EGFR P00533 1/20 0.55
LCK P06239 1/20 0.55
FYN P06241 1/20 0.55
ADORA3 P0DMS8 1/20 0.55
ALOX15 P16050 1/20 0.55
HTR2A P28223 1/20 0.55
PTGS2 P35354 1/20 0.55
RECQL P46063 1/20 0.55
HIF1A Q16665 1/20 0.55
HSD17B10 Q99714 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7975865 0.98 SLC7A5 (0.57) SLC7A5PTGS1PKMALPIXIAP
Anthraquinone SCHEMBL27984231 0.85 SLC7A5 (0.81) SLC7A5PTGS1PKMALPIXIAP
SCHEMBL7973837 0.81 MAPT (0.53) PKMSLC1A3SLC1A2SLC1A1KDM4E
Hydrochloric Acid SCHEMBL7973836 0.80 MAPT (0.51) PKMSLC1A3SLC1A2SLC1A1KDM4E
SCHEMBL30163256 0.78 SLC7A5 (0.80) SLC7A5PTGS1PKMALPIXIAP
SCHEMBL27630119 0.78 SLC7A5 (0.69) SLC7A5PTGS1PKMALPIXIAP
SCHEMBL2219303 0.78 SLC1A3 (0.60) SLC7A5PTGS1PKMALPIXIAP
SCHEMBL2219306 0.78 SLC1A3 (0.60) SLC7A5PTGS1PKMALPIXIAP
SCHEMBL12142781 0.78 SLC7A5 (0.51) SLC7A5PTGS1PKMALPIXIAP
SCHEMBL2767910 0.77 SLC7A5 (0.77) SLC7A5PTGS1PKMALPIXIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001077095-A2 DERIVATIVES OF ALPHA-MERCAPTOACETAMIDE NOVARTIS AG (CH) 2001-10-18 WO disclosed