SCHEMBL2767910

SCHEMBL2767910

N[C@@H](Cc1ccc(O)c(-c2cc(C[C@H](N)C(=O)O)ccc2O)c1)C(=O)O

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 5/20 0.77
USP2 O75604 3/20 0.77
PTGS1 P23219 2/20 0.77
KDM4E B2RXH2 2/20 0.77
ALOX15 P16050 2/20 0.77
RECQL P46063 2/20 0.77
HIF1A Q16665 2/20 0.77
HSD17B10 Q99714 2/20 0.77
TDP1 Q9NUW8 2/20 0.77
EGFR P00533 1/20 0.77
LCK P06239 1/20 0.77
FYN P06241 1/20 0.77
ADORA3 P0DMS8 1/20 0.77
HTR2A P28223 1/20 0.77
PTGS2 P35354 1/20 0.77
PKM P14618 3/20 0.56
ALPI P09923 1/20 0.56
XIAP P98170 1/20 0.56
GRIA2 P42262 1/20 0.54
THRB P10828 4/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29508389 1.00 SLC7A5 (0.77) SLC7A5USP2PTGS1KDM4EALOX15
SCHEMBL338068 1.00 SLC7A5 (0.77) SLC7A5USP2PTGS1KDM4EALOX15
SCHEMBL29364864 0.94 SLC7A5 (0.69) SLC7A5USP2PTGS1KDM4EALOX15
SCHEMBL9924695 0.94 SLC7A5 (0.69) SLC7A5USP2PTGS1KDM4EALOX15
SCHEMBL13588692 0.91 SLC7A5 (0.65) SLC7A5USP2PTGS1KDM4EALOX15
Levodopa SCHEMBL22655 0.87 SLC7A5 (1.00) SLC7A5USP2PTGS1KDM4EALOX15
Levodopa SCHEMBL704089 0.87 SLC7A5 (1.00) SLC7A5USP2PTGS1KDM4EALOX15
Levodopa SCHEMBL29975814 0.87 SLC7A5 (1.00) SLC7A5USP2PTGS1KDM4EALOX15
Levodopa SCHEMBL20582239 0.87 SLC7A5 (1.00) SLC7A5USP2PTGS1KDM4EALOX15
Levodopa SCHEMBL11000382 0.87 SLC7A5 (1.00) SLC7A5USP2PTGS1KDM4EALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190100784-A1 RNA ANALYSIS BY TOTAL HYDROLYSIS CureVac SE (DE) 2019-04-04 US claimed
EP-3423595-A1 RNA ANALYSIS BY TOTAL HYDROLYSIS CureVac AG (DE) 2019-01-09 EP claimed
US-11920174-B2 RNA analysis by total hydrolysis and quantification of released nucleosides CureVac SE (DE) 2024-03-05 US disclosed
US-20190100784-A1 RNA ANALYSIS BY TOTAL HYDROLYSIS CureVac SE (DE) 2019-04-04 US disclosed
EP-3439683-A1 IMMUNE SYSTEM MODULATION FOR PROPHYLAXIS AND TREATMENT OF DISEASES AND DISORDERS Marpe Holdings, LLC (US) 2019-02-13 EP disclosed
EP-3423595-A1 RNA ANALYSIS BY TOTAL HYDROLYSIS CureVac AG (DE) 2019-01-09 EP disclosed
WO-2017176757-A1 IMMUNE SYSTEM MODULATION FOR PROPHYLAXIS AND TREATMENT OF DISEASES AND DISORDERS Marpe Holdings, LLC (US) 2017-10-12 WO disclosed
US-20170283460-A1 Immune System Modulation for Prophylaxis and Treatment of Diseases and Disorders Marpe Holdings, LLC (US) 2017-10-05 US disclosed
US-9340595-B2 Crosslinking within coordination complexes UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2016-05-17 US disclosed
US-9328163-B2 Post-translationally modified neurotrophin antibodies INSTITUT PASTEUR (FR) 2016-05-03 US disclosed
US-20140294724-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF PROTEINOPATHIES INTELLECT NEUROSCIENCES, INC. (US) 2014-10-02 US disclosed
US-20090297538-A1 NEUROTOXIC OLIGOMERS PRANA BIOTECHNOLOGY LIMITED (AU) 2009-12-03 US disclosed
US-7618634-B2 Alzheimer's disease, Prkinson's disease, vision defects therapy; tyrosine crosslinked protein PRANA BIOTECHNOLOGY LIMITED (AU) 2009-11-17 US disclosed
EP-2046823-A1 POST-TRANSLATIONALLY MODIFIED NEUROTROPHINS Institut Pasteur (FR) 2009-04-15 EP disclosed
EP-1668067-A4 CROSSLINKING WITHIN COORDINATION COMPLEXES UNIV UTAH RES FOUND (US) 2008-10-22 EP disclosed
WO-2008012049-A1 POST-TRANSLATIONALLY MODIFIED NEUROTROPHINS INSTITUT PASTEUR (FR) 2008-01-31 WO disclosed
EP-1882697-A1 Post-translationally modified neurotrophins INSTITUT PASTEUR (FR) 2008-01-30 EP disclosed
EP-1668067-A2 CROSSLINKING WITHIN COORDINATION COMPLEXES The University of Utah Research Foundation (US) 2006-06-14 EP disclosed
WO-2005019421-A2 CROSSLINKING WITHIN COORDINATION COMPLEXES UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2005-03-03 WO disclosed
US-20040013680-A1 Neurotoxic oligomers THE GENERAL HOSPITAL CORPORATION 2004-01-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140294724-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF PROTEINOPATHIES CLN6, PSMG3, PSEN1 SLC7A5 3719/4885USP2 1522/4885PTGS1 4290/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.