Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.53 |
| ▸ | LMNA | P02545 | 7/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | GABRP | O00591 | 1/20 | 0.46 |
| ▸ | GABRD | O14764 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7973836 | 0.99 | MAPT (0.51) | MAPTALDH1A1LMNASMN1; SMN2NPC1 | |
| SCHEMBL7973704 | 0.81 | SLC7A5 (0.59) | MAPTALDH1A1LMNASMN1; SMN2NPC1 | |
| SCHEMBL7972265 | 0.81 | GABRP (0.47) | MAPTALDH1A1LMNASMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL7975865 | 0.80 | SLC7A5 (0.57) | MAPTALDH1A1LMNASMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL7972261 | 0.80 | GABRP (0.46) | MAPTALDH1A1LMNASMN1; SMN2NPC1 | |
| SCHEMBL839749 | 0.79 | HTR2A (0.55) | SLC1A3SLC1A2SLC1A1CYP1A2 | |
| SCHEMBL839943 | 0.79 | HTR2A (0.55) | SLC1A3SLC1A2SLC1A1CYP1A2 | |
| SCHEMBL7960935 | 0.79 | SLC7A5 (0.48) | ALDH1A1PKM | |
| SCHEMBL132409 | 0.78 | ALPI (0.61) | ALDH1A1NPC1MEN1KMT2APKM | |
| SCHEMBL616963 | 0.78 | ALPI (0.61) | ALDH1A1NPC1MEN1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001077095-A2 | DERIVATIVES OF ALPHA-MERCAPTOACETAMIDE | NOVARTIS AG (CH) | 2001-10-18 | — | — | WO | disclosed |