Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.50 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.49 |
| ▸ | MAPT | P10636 | 9/20 | 0.49 |
| ▸ | GAA | P10253 | 9/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.49 |
| ▸ | NPC1 | O15118 | 7/20 | 0.49 |
| ▸ | RAB9A | P51151 | 7/20 | 0.49 |
| ▸ | POLB | P06746 | 6/20 | 0.49 |
| ▸ | GLA | P06280 | 4/20 | 0.49 |
| ▸ | GFER | P55789 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.49 |
| ▸ | RECQL | P46063 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 7/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | BLM | P54132 | 4/20 | 0.47 |
| ▸ | USP2 | O75604 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10140073 | 0.85 | PTGDR2 (0.49) | POLBSMN1; SMN2CHEK2F9F10 | |
| SCHEMBL10140083 | 0.77 | F10 (0.60) | CHEK2F9F10F11 | |
| SCHEMBL7960334 | 0.77 | MEN1 (0.62) | MEN1KMT2ARXFP1CACNA1BAPBA1 | |
| SCHEMBL10139885 | 0.76 | MAPT (0.60) | MEN1KMT2ARXFP1CACNA1BAPBA1 | |
| SCHEMBL7970550 | 0.74 | F9 (0.46) | CHEK2NT5EF9F10F11 | |
| SCHEMBL10139891 | 0.71 | CHEK2 (0.69) | CHEK2F9F10F11 | |
| SCHEMBL7969006 | 0.71 | NPBWR1 (0.42) | CHEK2NT5EF9F10F11 | |
| SCHEMBL10140814 | 0.70 | PKN1 (0.50) | CHEK2F9F10F11 | |
| SCHEMBL2251258 | 0.69 | MEN1 (1.00) | MEN1KMT2ARXFP1CACNA1BAPBA1 | |
| SCHEMBL10139808 | 0.69 | P2RY6 (0.53) | ALDH1A1MAPTGAAKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143039-A2 | HETEROCYCLIC COMPOUNDS AS FACTOR IXA INHIBITORS | SCHERING CORPORATION (US) | 2009-11-26 | — | — | WO | disclosed |