Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.62 |
| ▸ | GAA | P10253 | 9/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.62 |
| ▸ | MAPT | P10636 | 8/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.62 |
| ▸ | NPC1 | O15118 | 6/20 | 0.62 |
| ▸ | RAB9A | P51151 | 6/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.62 |
| ▸ | HPGD | P15428 | 6/20 | 0.62 |
| ▸ | TP53 | P04637 | 3/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.62 |
| ▸ | APP | P05067 | 1/20 | 0.62 |
| ▸ | SNCA | P37840 | 1/20 | 0.62 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.62 |
| ▸ | RELA | Q04206 | 1/20 | 0.62 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.62 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.51 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10139885 | 0.89 | MAPT (0.60) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL7971481 | 0.86 | HIF1A (0.46) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL10139883 | 0.85 | CHEK2 (0.65) | MEN1KMT2ATHRBCHEK2 | |
| SCHEMBL10139878 | 0.84 | CHEK2 (0.65) | MEN1KMT2AMAPTTHRBTDP1 | |
| SCHEMBL10140455 | 0.84 | AMY1A (0.44) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL7971500 | 0.84 | PTGDR2 (0.49) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL10139961 | 0.80 | GUSB (0.39) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL10139884 | 0.79 | F10 (0.48) | CHEK2 | |
| SCHEMBL26731643 | 0.78 | MEN1 (1.00) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL7971397 | 0.78 | ALDH1A1 (0.39) | MEN1KMT2AGAAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143039-A2 | HETEROCYCLIC COMPOUNDS AS FACTOR IXA INHIBITORS | SCHERING CORPORATION (US) | 2009-11-26 | — | — | WO | disclosed |