Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRK6 | P43250 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 11/20 | 0.49 |
| ▸ | NPC1 | O15118 | 10/20 | 0.49 |
| ▸ | MAPT | P10636 | 9/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.48 |
| ▸ | RELA | Q04206 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7993840 | 0.88 | GRK6 (0.50) | GRK6RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL7972175 | 0.77 | GAA (0.59) | GRK6RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL5733947 | 0.77 | GAA (0.75) | GRK6MAPTKDM4EHSD17B10MEN1 | |
| SCHEMBL23176649 | 0.76 | KDM4E (0.53) | GRK6RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL26553778 | 0.76 | MEN1 (0.53) | GRK6RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL5736775 | 0.76 | GAA (0.48) | GRK6RAB9ANPC1MAPTMEN1 | |
| SCHEMBL5734523 | 0.75 | ACLY (0.44) | GRK6RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL7997880 | 0.75 | ESR1 (0.50) | GRK6RAB9ANPC1MAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL25400160 | 0.75 | MEN1 (0.52) | GRK6RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL4905164 | 0.75 | LOXL2 (0.55) | GRK6RAB9ANPC1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001055143-A1 | BENZOXAZOLE DERIVATIVES AND THEIR USE AS PESTICIDES | SYNGENTA LIMITED (GB) | 2001-08-02 | — | — | WO | disclosed |
| WO-2001055136-A1 | BENZOXAZOLE DERIVATIVES AND THEIR USE AS PESTICIDES | SYNGENTA LIMITED (GB) | 2001-08-02 | — | — | WO | disclosed |