Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 14/20 | 0.85 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.85 |
| ▸ | HPGD | P15428 | 2/20 | 0.85 |
| ▸ | TP53 | P04637 | 5/20 | 0.82 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.76 |
| ▸ | LMNA | P02545 | 3/20 | 0.70 |
| ▸ | RORC | P51449 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.63 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4728756 | 0.92 | MAPT (1.00) | MAPTKDM4EHPGDTP53SMN1; SMN2 | |
| SCHEMBL7974774 | 0.82 | MAPT (0.59) | MAPTKDM4EHPGDTP53SMN1; SMN2 | |
| SCHEMBL19189749 | 0.81 | RORC (0.87) | MAPTKDM4EHPGDTP53SMN1; SMN2 | |
| SCHEMBL7722834 | 0.81 | MAPT (0.81) | MAPTKDM4EHPGDTP53SMN1; SMN2 | |
| SCHEMBL14199692 | 0.81 | MAPT (0.82) | MAPTKDM4EHPGDSMN1; SMN2LMNA | |
| SCHEMBL6226561 | 0.81 | MAPT (0.74) | MAPTKDM4EHPGDSMN1; SMN2LMNA | |
| SCHEMBL14802073 | 0.80 | RORC (1.00) | MAPTKDM4EHPGDTP53SMN1; SMN2 | |
| SCHEMBL29900796 | 0.80 | RORC (1.00) | MAPTKDM4EHPGDTP53SMN1; SMN2 | |
| SCHEMBL4729061 | 0.79 | RORC (0.70) | MAPTKDM4EHPGDTP53SMN1; SMN2 | |
| SCHEMBL1593423 | 0.79 | MAPT (0.79) | MAPTKDM4EHPGDSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |