Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 14/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 1.00 |
| ▸ | HPGD | P15428 | 3/20 | 1.00 |
| ▸ | TP53 | P04637 | 5/20 | 0.84 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.74 |
| ▸ | LMNA | P02545 | 3/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | RORC | P51449 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.67 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7973755 | 0.92 | MAPT (0.85) | MAPTKDM4EHPGDTP53SMN1; SMN2 | |
| SCHEMBL7722834 | 0.84 | MAPT (0.81) | MAPTKDM4EHPGDTP53SMN1; SMN2 | |
| SCHEMBL14199692 | 0.84 | MAPT (0.82) | MAPTKDM4EHPGDSMN1; SMN2LMNA | |
| SCHEMBL14802073 | 0.82 | RORC (1.00) | MAPTKDM4EHPGDTP53SMN1; SMN2 | |
| SCHEMBL29900796 | 0.82 | RORC (1.00) | MAPTKDM4EHPGDTP53SMN1; SMN2 | |
| SCHEMBL4728393 | 0.82 | KDM4E (0.83) | MAPTKDM4EHPGDSMN1; SMN2LMNA | |
| SCHEMBL4728842 | 0.82 | NPY5R (0.83) | MAPTKDM4EHPGDTP53SMN1; SMN2 | |
| SCHEMBL4728399 | 0.82 | KDM4E (0.83) | MAPTKDM4EHPGDSMN1; SMN2LMNA | |
| SCHEMBL4729061 | 0.82 | RORC (0.70) | MAPTKDM4EHPGDTP53SMN1; SMN2 | |
| SCHEMBL4863449 | 0.82 | MAPT (0.79) | MAPTKDM4EHPGDSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021745-A2 | HEPATITIS C VIRUS ENTRY INHIBITORS | ITHERX PHARMACEUTICALS, INC. (US) | 2008-02-21 | — | — | WO | disclosed |
| EP-1395578-A1 | CARBAZOLE DERIVATIVES AND THEIR USE FOR THE PREPARATION OF PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF NPY RELATED DISEASES | BOEHRINGER INGELHEIM INTERNATIONAL GmbH (DE) | 2004-03-10 | — | — | EP | disclosed |
| WO-2002096902-A1 | CARBAZOLE DERIVATIVES AND THEIR USE FOR THE PREPARATION OF PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF NPY RELATED DISEASES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2002-12-05 | — | — | WO | disclosed |