Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.56 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.56 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | HRH1 | P35367 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | HTR2B | P41595 | 1/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | RAD52 | P43351 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14960116 | 0.92 | KAT2B (0.59) | KAT2BSMN1; SMN2CHRM2CHRM1DRD2 | |
| SCHEMBL29504306 | 0.91 | ALDH1A1 (0.65) | KAT2BSMN1; SMN2KMT2AALDH1A1NPSR1 | |
| SCHEMBL972656 | 0.91 | ALDH1A1 (0.65) | KAT2BSMN1; SMN2KMT2AALDH1A1NPSR1 | |
| SCHEMBL7170020 | 0.85 | KAT2B (0.81) | KAT2BSMN1; SMN2KMT2AALDH1A1MAPT | |
| SCHEMBL6200169 | 0.85 | KAT2B (0.81) | KAT2BSMN1; SMN2KMT2AALDH1A1MAPT | |
| SCHEMBL11720943 | 0.84 | KAT2B (0.61) | KAT2BSMN1; SMN2ALDH1A1MAPTNPC1 | |
| SCHEMBL8720672 | 0.84 | KAT2B (0.78) | KAT2BSMN1; SMN2KMT2AALDH1A1MAPT | |
| SCHEMBL6198359 | 0.84 | KAT2B (0.78) | KAT2BSMN1; SMN2KMT2AALDH1A1MAPT | |
| SCHEMBL981345 | 0.83 | KAT2B (0.71) | KAT2BSMN1; SMN2KMT2AALDH1A1MAPT | |
| SCHEMBL5922386 | 0.83 | KAT2B (0.71) | KAT2BSMN1; SMN2KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204264-B1 | Benzimidazole derivative, hair growth promoter and external composition for skin using the same | SHISEIDO CO., LTD. (JP) | 2001-03-20 | — | — | US | disclosed |
| EP-0989123-A1 | Benzimidazole derivative, hair growth promoter and external composition for skin using the same | SHISEIDO COMPANY LIMITED (JP) | 2000-03-29 | — | — | EP | disclosed |
| US-4059584-A | ANTIINFLAMMATORY | PFIZER (US) | 1977-11-22 | — | — | US | disclosed |
| US-4053472-A | MICROBIOCIDES | SCHERING AKTIENGESELLSCHAFT (DT) | 1977-10-11 | — | — | US | disclosed |
| US-4002623-A | Anti-inflammatory 1-[3-(dialkylamino)propyl]-2-acylaminobenzimidazoles and 2-acylamino-3-[3-(dialkylamino)-propyl]imidazo[4,5-b]pyridines | PFIZER INC. (US) | 1977-01-11 | — | — | US | disclosed |