Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29504306 | 1.00 | ALDH1A1 (0.65) | ALDH1A1NPSR1KAT2BMAPTSMN1; SMN2 | |
| SCHEMBL7973853 | 0.91 | KAT2B (0.66) | ALDH1A1NPSR1KAT2BMAPTSMN1; SMN2 | |
| SCHEMBL14960116 | 0.86 | KAT2B (0.59) | ALDH1A1NPSR1KAT2BMAPTSMN1; SMN2 | |
| SCHEMBL16655113 | 0.85 | KAT2B (0.57) | ALDH1A1NPSR1KAT2BMAPTSMN1; SMN2 | |
| SCHEMBL8985609 | 0.84 | KAT2B (0.57) | ALDH1A1NPSR1KAT2BMAPTSMN1; SMN2 | |
| SCHEMBL6198859 | 0.84 | KAT2B (0.80) | ALDH1A1KAT2BMAPTSMN1; SMN2NPC1 | |
| SCHEMBL4077151 | 0.81 | KAT2B (0.66) | ALDH1A1KAT2BMAPTSMN1; SMN2NPC1 | |
| SCHEMBL7170020 | 0.81 | KAT2B (0.81) | ALDH1A1KAT2BMAPTSMN1; SMN2NPC1 | |
| SCHEMBL6200169 | 0.81 | KAT2B (0.81) | ALDH1A1KAT2BMAPTSMN1; SMN2NPC1 | |
| SCHEMBL9725410 | 0.80 | ALDH1A1 (0.72) | ALDH1A1NPSR1KAT2BMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020240492-A1 | 1,3,4-OXADIAZOLE DERIVATIVE COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND THE PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2020-12-03 | — | — | WO | disclosed |
| EP-3057943-A1 | PYRIMIDINE FGFR4 INHIBITORS | Eisai R&D Management Co., Ltd. (JP) | 2016-08-24 | — | — | EP | disclosed |
| WO-2015057938-A1 | PYRIMIDINE FGFR4 INHIBITORS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2015-04-23 | — | — | WO | disclosed |
| EP-2178861-B1 | HETEROCYCLIC AMIDE COMPOUNDS AS PROTEIN KINASE INHIBITORS | MERCK SHARP & DOHME (US) | 2014-08-20 | — | — | EP | disclosed |
| US-8293747-B2 | Heterocyclic amide compounds as protein kinase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2012-10-23 | — | — | US | disclosed |
| US-7868177-B2 | Multi-cyclic compounds and method of use | AMGEN INC. (US) | 2011-01-11 | — | — | US | disclosed |
| US-20100286135-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS PROTEIN KINASE INHIBITORS | Schering Corporation Patent Department, K-6-1; 1990 (US) | 2010-11-11 | — | — | US | disclosed |
| EP-1994030-B1 | MULTI-CYCLIC COMPOUNDS AND METHOD OF USE | AMGEN INC (US) | 2010-08-25 | — | — | EP | disclosed |
| US-7544701-B2 | Sulfonyldihydrobenzimidazolone compounds as 5-hydroxytryptamine-6 ligands | WYETH (US) | 2009-06-09 | — | — | US | disclosed |
| US-7544701-B2 | Sulfonyldihydrobenzimidazolone compounds as 5-hydroxytryptamine-6 ligands | WYETH (US) | 2009-06-09 | — | — | US | disclosed |
| US-6468316-B1 | DIRECT DYES HAVING COLORFASTNESS AND SOLUBILITY, USED FOR HUMAN HAIR | L'OREAL S.A. (FR) | 2002-10-22 | — | — | US | disclosed |
| US-6379398-B1 | AROMATIC DIAMINES AS HAIR DYES | L'OREAL (FR) | 2002-04-30 | — | — | US | disclosed |
| US-6153120-A | Bleaching compositions | THE PROCTER & GAMBLE COMPANY (US) | 2000-11-28 | — | — | US | disclosed |
| EP-1020176-A2 | Use of cationic bis-nitrobenzenes for dyeing of keratinic fibers, dyeing compositions and dyeing process | L'OREAL (FR) | 2000-07-19 | — | — | EP | disclosed |
| EP-0984006-A1 | Cationic compounds, their use for the oxidation dyeing of keratinous fibres, dyeing compositions and dyeing methods | L'OREAL (FR) | 2000-03-08 | — | — | EP | disclosed |
| EP-0983996-A1 | Cationic ortho-phenylenediamines, their use for oxidation dyeing of keratinous fibres, dyeing compositions and dyeing methods | L'OREAL (FR) | 2000-03-08 | — | — | EP | disclosed |
| US-5256823-A | Lightfast yellow dyes | CLAIROL INCORPORATED (US) | 1993-10-26 | — | — | US | disclosed |
| US-5162318-A | Which have pulmonary surfactant secretion promoting activity | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1992-11-10 | — | — | US | disclosed |
| US-5135543-A | Lightfast blends; natural shades of yellow with sun exposure | CLAIROL INCORPORATED (US) | 1992-08-04 | — | — | US | disclosed |
| EP-0454330-A1 | Benzimidazolinone derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-10-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286135-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS PROTEIN KINASE INHIBITORS | MTOR, CDK1, MAP3K8 | ALDH1A1 2293/4885NPSR1 2486/4885KAT2B 534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.