Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ACP1 | P24666 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.36 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.36 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985425 | 0.89 | ACP1 (0.42) | LMNAPOLBSMN1; SMN2ACP1MEN1 | |
| SCHEMBL7975267 | 0.86 | SMN1; SMN2 (0.46) | ALDH1A1LMNASMN1; SMN2KMT2ACASP3 | |
| SCHEMBL7987222 | 0.85 | PDE4A (0.49) | ALDH1A1LMNAPOLBRAB9AATM | |
| SCHEMBL7984788 | 0.85 | CYP11B1 (0.45) | L3MBTL1ALDH1A1LMNAPOLBRAB9A | |
| SCHEMBL7991405 | 0.84 | CYP11B1 (0.45) | ALDH1A1LMNASMN1; SMN2PDE5AKMT2A | |
| SCHEMBL7984459 | 0.81 | NR1H2 (0.43) | ALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL7986521 | 0.81 | CYP11B1 (0.47) | L3MBTL1ALDH1A1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL7984717 | 0.81 | SMN1; SMN2 (0.46) | ALDH1A1LMNAPOLBRAB9ASMN1; SMN2 | |
| SCHEMBL7988668 | 0.80 | SMN1; SMN2 (0.44) | L3MBTL1ALDH1A1SMN1; SMN2ACP1PDE5A | |
| SCHEMBL7988558 | 0.80 | SMN1; SMN2 (0.43) | ALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |