Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | PARN | O95453 | 1/20 | 0.38 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991405 | 0.95 | CYP11B1 (0.45) | NR1H2NR1H3SMN1; SMN2ALDH1A1CYP11B1 | |
| SCHEMBL7975267 | 0.92 | SMN1; SMN2 (0.46) | NR1H3SMN1; SMN2ALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL7988558 | 0.91 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1CYP11B1CYP11B2HPGD | |
| SCHEMBL7975133 | 0.90 | ADORA2A (0.50) | SMN1; SMN2ALDH1A1CYP11B1CYP11B2HPGD | |
| Hydrochloric Acid SCHEMBL7985515 | 0.89 | ADORA2A (0.49) | SMN1; SMN2ALDH1A1CYP11B1CYP11B2HPGD | |
| SCHEMBL7974507 | 0.89 | MET (0.46) | SMN1; SMN2ALDH1A1CYP11B1CYP11B2HPGD | |
| SCHEMBL7988668 | 0.88 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1CYP11B1CYP11B2MAPK1 | |
| SCHEMBL7974441 | 0.88 | GRK2 (0.43) | SMN1; SMN2ALDH1A1CYP11B1CYP11B2HPGD | |
| SCHEMBL7974012 | 0.87 | ALDH1A1 (0.41) | SMN1; SMN2ALDH1A1CYP11B1CYP11B2HTT | |
| SCHEMBL7974458 | 0.86 | ADORA2A (0.44) | SMN1; SMN2ALDH1A1HPGDADORA2AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |