Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7976401 | 0.90 | POLB (0.46) | ALDH1A1SMN1; SMN2POLBTSHRLMNA | |
| SCHEMBL7978959 | 0.89 | SMN1; SMN2 (0.48) | ALDH1A1SMN1; SMN2POLBTSHRLMNA | |
| SCHEMBL7962709 | 0.84 | KMT2A (0.44) | ALDH1A1SMN1; SMN2POLBTSHRLMNA | |
| SCHEMBL7972625 | 0.82 | KMT2A (0.42) | ALDH1A1SMN1; SMN2POLBTSHRKMT2A | |
| SCHEMBL7976498 | 0.81 | KMT2A (0.44) | ALDH1A1SMN1; SMN2POLBTSHRKDM4E | |
| SCHEMBL7972624 | 0.81 | KMT2A (0.41) | ALDH1A1SMN1; SMN2POLBTSHRKMT2A | |
| SCHEMBL7976446 | 0.80 | HTT (0.42) | ALDH1A1SMN1; SMN2POLBTSHRLMNA | |
| SCHEMBL11061527 | 0.80 | KMT2A (0.49) | ALDH1A1SMN1; SMN2POLBTSHRLMNA | |
| SCHEMBL25448081 | 0.80 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2TSHRLMNAGAA | |
| SCHEMBL7976398 | 0.79 | KMT2A (0.42) | ALDH1A1SMN1; SMN2POLBTSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6268511-B1 | USED FOR PRODUCING COPOLYMER WITH ACRYLIC ESTER COMONOMERS; COPOLYMERS ARE USED FOR FOLDABLE INTRAOCULAR LENSES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2001-07-31 | — | — | US | disclosed |
| EP-0987247-A1 | ITACONATE DERIVATIVES USED FOR A COMPONENT OF A POLYMER | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2000-03-22 | — | — | EP | disclosed |