Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7976401 | 0.90 | POLB (0.46) | HTTLMNAALDH1A1SMN1; SMN2GAA | |
| SCHEMBL7962709 | 0.89 | KMT2A (0.44) | LMNAALDH1A1SMN1; SMN2GAAL3MBTL1 | |
| SCHEMBL7978959 | 0.84 | SMN1; SMN2 (0.48) | LMNAALDH1A1SMN1; SMN2POLBTSHR | |
| SCHEMBL7974160 | 0.80 | ALDH1A1 (0.45) | HTTLMNAALDH1A1SMN1; SMN2GAA | |
| SCHEMBL8812410 | 0.79 | TDP1 (0.54) | LMNAALDH1A1SMN1; SMN2L3MBTL1TSHR | |
| SCHEMBL7978944 | 0.79 | KMT2A (0.40) | HTTALDH1A1SMN1; SMN2GAAL3MBTL1 | |
| SCHEMBL7978942 | 0.76 | KMT2A (0.40) | HTTLMNAALDH1A1SMN1; SMN2GAA | |
| SCHEMBL7962678 | 0.76 | KMT2A (0.44) | HTTLMNAALDH1A1SMN1; SMN2GAA | |
| SCHEMBL15122553 | 0.74 | MEN1 (0.49) | ALDH1A1SMN1; SMN2GAATSHRTDP1 | |
| SCHEMBL7974068 | 0.73 | TDP1 (0.56) | LMNAALDH1A1SMN1; SMN2L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6268511-B1 | USED FOR PRODUCING COPOLYMER WITH ACRYLIC ESTER COMONOMERS; COPOLYMERS ARE USED FOR FOLDABLE INTRAOCULAR LENSES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2001-07-31 | — | — | US | disclosed |
| EP-0987247-A1 | ITACONATE DERIVATIVES USED FOR A COMPONENT OF A POLYMER | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2000-03-22 | — | — | EP | disclosed |