Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
| ▸ | PARN | O95453 | 1/20 | 0.38 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985463 | 0.90 | HPGD (0.52) | HPGDSMN1; SMN2ALDH1A1KMT2ABRD4 | |
| SCHEMBL7974180 | 0.85 | CNOT7 (0.44) | HPGDSMN1; SMN2ALDH1A1BRD4MCL1 | |
| SCHEMBL7988916 | 0.84 | HPGD (0.50) | HPGDSMN1; SMN2ALDH1A1KMT2ABRD4 | |
| SCHEMBL7974033 | 0.83 | HPGD (0.49) | HPGDSMN1; SMN2ALDH1A1KMT2ABRD4 | |
| SCHEMBL7974177 | 0.82 | MCL1 (0.41) | HPGDSMN1; SMN2ALDH1A1KMT2AMCL1 | |
| SCHEMBL7988125 | 0.81 | HPGD (0.43) | HPGDSMN1; SMN2ALDH1A1KMT2AMCL1 | |
| SCHEMBL7987946 | 0.81 | HPGD (0.42) | HPGDSMN1; SMN2ALDH1A1KMT2ABRD4 | |
| SCHEMBL7991429 | 0.81 | HPGD (0.55) | HPGDSMN1; SMN2ALDH1A1KMT2ABRD4 | |
| SCHEMBL7985320 | 0.81 | LMNA (0.47) | HPGDSMN1; SMN2ALDH1A1MCL1CNOT7 | |
| SCHEMBL7991611 | 0.81 | HPGD (0.42) | HPGDSMN1; SMN2ALDH1A1KMT2AMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |