Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.36 |
| ▸ | PARN | O95453 | 1/20 | 0.36 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.36 |
| ▸ | PNP | P00491 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988916 | 0.95 | HPGD (0.50) | HPGDSMN1; SMN2ALDH1A1KMT2ACCNE2 | |
| SCHEMBL7985463 | 0.89 | HPGD (0.52) | HPGDSMN1; SMN2ALDH1A1KMT2AHTR2C | |
| SCHEMBL7974030 | 0.86 | CNOT7 (0.42) | HPGDSMN1; SMN2ALDH1A1CCNE2CCNE1 | |
| SCHEMBL7985298 | 0.83 | ALDH1A1 (0.52) | HPGDSMN1; SMN2ALDH1A1KMT2APARN | |
| SCHEMBL7974183 | 0.83 | HPGD (0.51) | HPGDSMN1; SMN2ALDH1A1KMT2AMCL1 | |
| SCHEMBL7985320 | 0.82 | LMNA (0.47) | HPGDSMN1; SMN2ALDH1A1HTR2CSLC6A4 | |
| SCHEMBL7974025 | 0.82 | HTR2C (0.39) | HPGDSMN1; SMN2ALDH1A1KMT2AHTR2C | |
| SCHEMBL7991611 | 0.82 | HPGD (0.42) | HPGDSMN1; SMN2ALDH1A1KMT2AHTR2C | |
| SCHEMBL7987946 | 0.81 | HPGD (0.42) | HPGDSMN1; SMN2ALDH1A1KMT2ACCNE2 | |
| SCHEMBL7991666 | 0.81 | SMN1; SMN2 (0.53) | HPGDSMN1; SMN2ALDH1A1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |