Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.37 |
| ▸ | PPARA | Q07869 | 5/20 | 0.37 |
| ▸ | FABP4 | P15090 | 2/20 | 0.34 |
| ▸ | FABP3 | P05413 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 5/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | EIF4E | P06730 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7521983 | 0.86 | PPARD (0.38) | PPARGPPARAFABP4S1PR5S1PR4 | |
| SCHEMBL7523563 | 0.83 | PPARD (0.39) | PPARGPPARAFABP4S1PR5S1PR4 | |
| SCHEMBL7962753 | 0.76 | PPARA (0.38) | PPARGPPARAFABP4KDM4EMEN1 | |
| SCHEMBL7976487 | 0.73 | PPARA (0.37) | PPARGPPARAMEN1ALDH1A1MAPT | |
| SCHEMBL7523867 | 0.72 | PPARD (0.40) | MEN1MAPTKMT2AEIF4ETP53 | |
| SCHEMBL7527935 | 0.70 | PPARD (0.41) | PPARGPPARAS1PR5S1PR4MEN1 | |
| SCHEMBL7974190 | 0.70 | PPARA (0.38) | PPARGPPARAFABP4S1PR5S1PR4 | |
| SCHEMBL7962722 | 0.68 | ADORA1 (0.38) | PPARGPPARAFABP4KDM4EMEN1 | |
| SCHEMBL7521850 | 0.67 | PPARA (0.37) | PPARGPPARAFABP4KDM4EALDH1A1 | |
| SCHEMBL7530733 | 0.67 | PTGIR (0.39) | KDM4EMEN1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248766-B1 | CARDIOVASCULAR DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-06-19 | — | — | US | disclosed |