Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.37 |
| ▸ | PPARG | P37231 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | EIF4E | P06730 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7962801 | 0.86 | PPARA (0.35) | PPARAPPARGMAPTMEN1KMT2A | |
| SCHEMBL7521160 | 0.85 | PTGDR2 (0.43) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL7976488 | 0.85 | MEN1 (0.33) | PPARAPPARGALDH1A1MAPTMEN1 | |
| SCHEMBL7974229 | 0.81 | MAPT (0.38) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL7974227 | 0.81 | MAPT (0.38) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL7521850 | 0.80 | PPARA (0.37) | PPARAPPARGALDH1A1MAPTKMT2A | |
| SCHEMBL7962804 | 0.79 | KMT2A (0.34) | PPARAPPARGALDH1A1MAPTMEN1 | |
| SCHEMBL7972424 | 0.77 | PPARA (0.37) | PPARAPPARGMAPTLMNAALOX5 | |
| SCHEMBL7518603 | 0.76 | PTGIR (0.41) | PPARAPPARGMAPTMEN1KMT2A | |
| SCHEMBL7976456 | 0.75 | PPARA (0.39) | PPARAPPARGMAPTKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248766-B1 | CARDIOVASCULAR DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-06-19 | — | — | US | disclosed |