Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 3/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | GBA1 | P04062 | 8/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.33 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27304848 | 0.82 | DDB1 (0.35) | DDB1CRBNMAOAMAOBGBA1 | |
| SCHEMBL17107930 | 0.82 | GBA1 (0.40) | GBA1 | |
| SCHEMBL22917018 | 0.79 | MAOA (0.35) | DDB1CRBNMAOAMAOBKCNJ1 | |
| SCHEMBL10862838 | 0.79 | DDB1 (0.33) | DDB1CRBNMAOAMAOBGBA1 | |
| SCHEMBL13471584 | 0.79 | — | — | |
| SCHEMBL22916908 | 0.79 | MAOA (0.33) | DDB1CRBNMAOAMAOBGBA1 | |
| SCHEMBL21322107 | 0.78 | CYP19A1 (0.40) | GBA1CYP19A1 | |
| SCHEMBL11948270 | 0.78 | — | — | |
| SCHEMBL23564883 | 0.77 | KCNJ1 (0.36) | DDB1CRBNMAOAMAOBGBA1 | |
| SCHEMBL17108728 | 0.77 | MC1R (0.35) | DDB1CRBNMAOAMAOBGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019189778-A1 | COMPOUND WITH ANTICANCER ACTIVITY | 協和発酵キリン株式会社 | 2019-10-03 | — | — | WO | disclosed |
| WO-2009141240-A1 | NOVEL DUAL TARGETING ANTITUMOURAL CONJUGATES | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2009-11-26 | — | — | WO | disclosed |