Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 3/20 | 0.33 |
| ▸ | BRD2 | P25440 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 5/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 6/20 | 0.31 |
| ▸ | MIF | P14174 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23564885 | 0.85 | KCNJ1 (0.35) | KCNJ1NOTUMDDB1CRBNBRD4 | |
| SCHEMBL23011899 | 0.82 | NOTUM (0.35) | NOTUM | |
| SCHEMBL16579400 | 0.79 | NOTUM (0.52) | KCNJ1NOTUMDDB1CRBNBRD4 | |
| SCHEMBL13233213 | 0.77 | DDB1 (0.39) | KCNJ1NOTUMDDB1CRBNBRD4 | |
| SCHEMBL7974222 | 0.77 | DDB1 (0.36) | KCNJ1DDB1CRBNBRD4MAOA | |
| SCHEMBL27304848 | 0.75 | DDB1 (0.35) | KCNJ1NOTUMDDB1CRBNMAOA | |
| SCHEMBL15336482 | 0.75 | KCNJ1 (0.41) | KCNJ1NOTUMDDB1CRBNBRD4 | |
| SCHEMBL11948270 | 0.74 | — | — | |
| SCHEMBL15791171 | 0.74 | DDX3X (0.41) | DDB1CRBNBRD4MAOAMAOB | |
| SCHEMBL13435235 | 0.73 | GLS (0.41) | KCNJ1NOTUMBRD4BRD2GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021126974-A1 | BIFUNCTIONAL AGENTS FOR PROTEIN RECRUITMENT AND/OR DEGRADATION | ORIONIS BIOSCIENCES, INC. (US) | 2021-06-24 | — | — | WO | disclosed |