Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.74 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | IDE | P14735 | 1/20 | 0.57 |
| ▸ | AANAT | Q16613 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974250 | 0.88 | MEN1 (0.77) | MEN1KMT2AMTNR1ACYP1A2CYP2D6 | |
| SCHEMBL7972523 | 0.88 | MEN1 (0.81) | MEN1KMT2AMTNR1ACYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL7960692 | 0.87 | MEN1 (0.79) | MEN1KMT2AMTNR1ACYP1A2CYP2D6 | |
| SCHEMBL1233177 | 0.83 | MEN1 (0.81) | MEN1KMT2AMTNR1ACYP1A2CYP2C19 | |
| SCHEMBL7973988 | 0.83 | MEN1 (0.71) | MEN1KMT2AMTNR1ACYP1A2HPGD | |
| Hydrochloric Acid SCHEMBL7960823 | 0.82 | MEN1 (0.71) | MEN1KMT2AMTNR1ACYP1A2CYP2D6 | |
| SCHEMBL5578012 | 0.82 | MEN1 (0.83) | MEN1KMT2AMTNR1ACYP1A2CYP2D6 | |
| SCHEMBL18607486 | 0.81 | MEN1 (0.77) | MEN1KMT2AMTNR1ACYP1A2CYP2D6 | |
| SCHEMBL4092371 | 0.81 | ALDH1A1 (0.75) | MEN1KMT2ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL24347579 | 0.81 | MEN1 (0.68) | MEN1KMT2AMTNR1ACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001055109-A1 | AROMATIC AMIDES ACTING ON MELANOCORTIN RECEPTORS | MELACURE THERAPEUTICS AB (SE) | 2001-08-02 | — | — | WO | claimed |
| WO-2001055109-A1 | AROMATIC AMIDES ACTING ON MELANOCORTIN RECEPTORS | MELACURE THERAPEUTICS AB (SE) | 2001-08-02 | — | — | WO | disclosed |