Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | FABP4 | P15090 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | XIAP | P98170 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | TACR3 | P29371 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7976456 | 0.89 | PPARA (0.39) | PPARAPPARGNPC1RAB9AALOX5 | |
| SCHEMBL7972708 | 0.85 | PPARA (0.39) | PPARAPPARGNPC1RAB9AALOX5 | |
| SCHEMBL7972424 | 0.83 | PPARA (0.37) | PPARAPPARGNPC1RAB9AALOX5 | |
| SCHEMBL7521850 | 0.83 | PPARA (0.37) | PPARAPPARGNPC1RAB9AALOX5 | |
| SCHEMBL7976474 | 0.82 | PPARA (0.36) | PPARAPPARGNPC1RAB9AALOX5 | |
| SCHEMBL7976455 | 0.81 | PPARA (0.36) | PPARAPPARGNPC1RAB9AALOX5 | |
| SCHEMBL7976492 | 0.80 | ALOX5 (0.38) | PPARAPPARGNPC1RAB9AALOX5 | |
| SCHEMBL7962788 | 0.80 | PPARA (0.35) | PPARAPPARGNPC1RAB9AALOX5 | |
| SCHEMBL7974210 | 0.80 | ADORA1 (0.41) | PPARAPPARGNPC1RAB9AFABP4 | |
| SCHEMBL7517921 | 0.79 | KDM4E (0.41) | NPC1RAB9APOLBSMN1; SMN2ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248766-B1 | CARDIOVASCULAR DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-06-19 | — | — | US | disclosed |