Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.36 |
| ▸ | PPARG | P37231 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TACR3 | P29371 | 1/20 | 0.31 |
| ▸ | XIAP | P98170 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7962804 | 0.92 | KMT2A (0.34) | PPARAPPARGNPC1RAB9AMAPT | |
| SCHEMBL7520084 | 0.83 | PTGIR (0.42) | NPC1RAB9ADHODHKDM4EPOLB | |
| SCHEMBL7974272 | 0.82 | PPARA (0.39) | PPARAPPARGNPC1RAB9AFABP4 | |
| SCHEMBL7976456 | 0.82 | PPARA (0.39) | PPARAPPARGNPC1RAB9AFABP4 | |
| SCHEMBL7521850 | 0.82 | PPARA (0.37) | PPARAPPARGNPC1RAB9AFABP4 | |
| SCHEMBL7972424 | 0.82 | PPARA (0.37) | PPARAPPARGNPC1RAB9AFABP4 | |
| SCHEMBL7521207 | 0.81 | PTGIR (0.39) | NPC1RAB9ALMNANPSR1 | |
| SCHEMBL7972708 | 0.80 | PPARA (0.39) | PPARAPPARGNPC1RAB9AFABP4 | |
| SCHEMBL7976455 | 0.80 | PPARA (0.36) | PPARAPPARGNPC1RAB9AFABP4 | |
| SCHEMBL7527902 | 0.80 | PTGIR (0.39) | DHODHPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248766-B1 | CARDIOVASCULAR DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-06-19 | — | — | US | disclosed |