Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ACP1 | P24666 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PARN | O95453 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984686 | 0.94 | CNOT7 (0.50) | CNOT7KDM4ELMNAPOLBMAPK1 | |
| SCHEMBL7984244 | 0.90 | CNOT7 (0.60) | CNOT7KDM4ELMNAPOLBMAPK1 | |
| SCHEMBL7985605 | 0.89 | CNOT7 (0.54) | CNOT7KDM4ELMNAPOLBMAPK1 | |
| SCHEMBL7987629 | 0.88 | CNOT7 (0.52) | CNOT7KDM4ELMNAPOLBMAPK1 | |
| SCHEMBL7986359 | 0.88 | CNOT7 (0.52) | CNOT7KDM4ELMNAPOLBMAPK1 | |
| SCHEMBL7992307 | 0.88 | CNOT7 (0.54) | CNOT7KDM4ELMNAPOLBMAPK1 | |
| SCHEMBL7987255 | 0.88 | PARN (0.48) | CNOT7MAPK1ACP1PIN1PARN | |
| SCHEMBL7984902 | 0.85 | CNOT7 (0.49) | CNOT7KDM4ELMNAPOLBMAPK1 | |
| SCHEMBL7991676 | 0.84 | ACP1 (0.43) | CNOT7ACP1PIN1PARN | |
| SCHEMBL7974290 | 0.84 | KDM4E (0.50) | CNOT7KDM4ELMNAPOLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |