Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 5/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
| ▸ | PARN | O95453 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7973875 | 0.94 | CNOT7 (0.53) | CNOT7MAPK1KDM4ELMNAPOLB | |
| SCHEMBL7984244 | 0.92 | CNOT7 (0.60) | CNOT7MAPK1KDM4ELMNAPOLB | |
| SCHEMBL7984493 | 0.89 | CNOT7 (0.54) | CNOT7MAPK1KDM4ELMNAPOLB | |
| SCHEMBL7974293 | 0.89 | CNOT7 (0.52) | CNOT7MAPK1KDM4ELMNAPOLB | |
| SCHEMBL7991656 | 0.88 | CNOT7 (0.55) | CNOT7MAPK1KDM4ELMNAPOLB | |
| SCHEMBL7974508 | 0.87 | CNOT7 (0.51) | CNOT7KDM4ELMNATNKSTNKS2 | |
| SCHEMBL7974620 | 0.85 | CNOT7 (0.58) | CNOT7MAPK1KDM4ELMNAPOLB | |
| SCHEMBL7984469 | 0.85 | CNOT7 (0.54) | CNOT7MAPK1KDM4ELMNAPOLB | |
| SCHEMBL7974048 | 0.83 | CNOT7 (0.53) | CNOT7MAPK1KDM4ELMNAPOLB | |
| SCHEMBL7985608 | 0.83 | LMNA (0.53) | CNOT7MAPK1KDM4ELMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |