Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 7/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PARN | O95453 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991656 | 0.93 | CNOT7 (0.55) | CNOT7KDM4ELMNAPOLBMAPK1 | |
| SCHEMBL7974620 | 0.93 | CNOT7 (0.58) | CNOT7KDM4ELMNAPOLBMAPK1 | |
| SCHEMBL7985605 | 0.92 | CNOT7 (0.54) | CNOT7KDM4ELMNAPOLBMAPK1 | |
| SCHEMBL7984493 | 0.92 | CNOT7 (0.54) | CNOT7KDM4ELMNAPOLBMAPK1 | |
| SCHEMBL7974048 | 0.90 | CNOT7 (0.53) | CNOT7KDM4ELMNAPOLBMAPK1 | |
| SCHEMBL7974293 | 0.90 | CNOT7 (0.52) | CNOT7KDM4ELMNAPOLBMAPK1 | |
| SCHEMBL7992307 | 0.90 | CNOT7 (0.54) | CNOT7KDM4ELMNAPOLBMAPK1 | |
| SCHEMBL7987629 | 0.90 | CNOT7 (0.52) | CNOT7KDM4ELMNAPOLBMAPK1 | |
| SCHEMBL7986359 | 0.90 | CNOT7 (0.52) | CNOT7KDM4ELMNAPOLBMAPK1 | |
| SCHEMBL7984902 | 0.87 | CNOT7 (0.49) | CNOT7KDM4ELMNAPOLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |