Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974325 | 0.85 | HTR1A (0.48) | HTR1AALDH1A1MEN1CYP3A4CYP2D6 | |
| SCHEMBL7961134 | 0.76 | HCAR2 (0.31) | — | |
| SCHEMBL29263737 | 0.74 | HPGD (0.59) | HTR1AALDH1A1HTR7HPGDDRD3 | |
| SCHEMBL3476989 | 0.73 | ACHE (0.81) | HTR1AHTR7KMT2ADRD3CYP1A2 | |
| SCHEMBL14450985 | 0.73 | ACHE (0.57) | HTR1AALDH1A1HTR7HPGDDRD3 | |
| SCHEMBL31128445 | 0.72 | HDAC8 (0.47) | ALDH1A1MEN1KMT2AHSD17B10KDM4E | |
| SCHEMBL8862878 | 0.72 | TDP1 (0.75) | MEN1KMT2ACYP1A2CYP2C19ACHE | |
| SCHEMBL6777483 | 0.72 | TDP1 (0.75) | MEN1KMT2ACYP1A2CYP2C19ACHE | |
| SCHEMBL8863154 | 0.72 | TDP1 (0.75) | MEN1KMT2ACYP1A2CYP2C19ACHE | |
| SCHEMBL2604742 | 0.72 | TDP1 (0.75) | MEN1KMT2ACYP1A2CYP2C19ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326369-B1 | ALZHEIMER'S DISEASE | TAKEDA CHEMICALS INDUSTRIES, LTD. (JP) | 2001-12-04 | — | — | US | disclosed |