Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.55 |
| ▸ | AR | P10275 | 7/20 | 0.53 |
| ▸ | NPC1 | O15118 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.49 |
| ▸ | RELA | Q04206 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974431 | 1.00 | SMN1; SMN2 (0.55) | SMN1; SMN2ARNPC1RAB9AHPGD | |
| SCHEMBL7974429 | 0.88 | AR (0.42) | SMN1; SMN2ARNPC1RAB9AHPGD | |
| SCHEMBL7964022 | 0.86 | AR (0.41) | SMN1; SMN2ARNPC1RAB9AHPGD | |
| SCHEMBL7964010 | 0.84 | SMN1; SMN2 (0.61) | SMN1; SMN2ARNPC1RAB9AHPGD | |
| SCHEMBL7964121 | 0.84 | SMN1; SMN2 (0.61) | SMN1; SMN2ARNPC1RAB9AHPGD | |
| SCHEMBL8915939 | 0.84 | NPC1 (0.56) | SMN1; SMN2ARNPC1RAB9AHPGD | |
| SCHEMBL8914247 | 0.84 | NPC1 (0.56) | SMN1; SMN2ARNPC1RAB9AHPGD | |
| SCHEMBL8914907 | 0.84 | NPC1 (0.56) | SMN1; SMN2ARNPC1RAB9AHPGD | |
| SCHEMBL8915335 | 0.84 | NPC1 (0.56) | SMN1; SMN2ARNPC1RAB9AHPGD | |
| SCHEMBL8915101 | 0.84 | NPC1 (0.56) | SMN1; SMN2ARNPC1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034573-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | claimed |
| WO-2001034573-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |