Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 7/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.37 |
| ▸ | RELA | Q04206 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2E1 | P05181 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP2C8 | P10632 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974429 | 0.87 | AR (0.42) | ARSMN1; SMN2RAB9ANPC1LMNA | |
| SCHEMBL7974426 | 0.86 | SMN1; SMN2 (0.55) | ARSMN1; SMN2RAB9ANPC1LMNA | |
| SCHEMBL7974431 | 0.86 | SMN1; SMN2 (0.55) | ARSMN1; SMN2RAB9ANPC1LMNA | |
| SCHEMBL7977451 | 0.84 | SMN1; SMN2 (0.39) | ARSMN1; SMN2RAB9ANPC1LMNA | |
| SCHEMBL7963868 | 0.84 | SMN1; SMN2 (0.42) | ARSMN1; SMN2RAB9ANPC1LMNA | |
| SCHEMBL7963854 | 0.74 | PDCD1 (0.37) | LMNAKMT2AALDH1A1HTTHPGD | |
| SCHEMBL7964015 | 0.73 | EPHX2 (0.64) | ARSMN1; SMN2RAB9ANPC1LMNA | |
| SCHEMBL7964032 | 0.72 | NPC1 (0.60) | ARSMN1; SMN2RAB9ANPC1LMNA | |
| SCHEMBL7964010 | 0.71 | SMN1; SMN2 (0.61) | ARSMN1; SMN2RAB9ANPC1LMNA | |
| SCHEMBL7964121 | 0.71 | SMN1; SMN2 (0.61) | ARSMN1; SMN2RAB9ANPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034573-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | claimed |
| WO-2001034573-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |