Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | PRKCI | P41743 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13201028 | 0.81 | ATR (0.61) | ATRMEN1KMT2APRKCIGAA | |
| SCHEMBL938982 | 0.80 | GRM4 (0.69) | ATRMEN1KMT2APRKCIGAA | |
| SCHEMBL5936350 | 0.80 | HTT (0.60) | ATRMEN1KMT2APRKCIGAA | |
| SCHEMBL5240286 | 0.80 | KDR (0.58) | ATRHTTKDRADORA3POLB | |
| SCHEMBL28276095 | 0.78 | PRKCI (0.63) | ATRMEN1KMT2ATDP1PRKCI | |
| SCHEMBL22980261 | 0.77 | PLK1 (0.45) | ALDH1A1MAPTKDM4ECYP3A4 | |
| SCHEMBL13139218 | 0.77 | PRKCI (0.67) | MEN1KMT2ATDP1PRKCIGAA | |
| SCHEMBL5709026 | 0.76 | TRPV1 (0.60) | ATRMEN1KMT2APRKCIGAA | |
| SCHEMBL12495392 | 0.76 | L3MBTL1 (0.59) | ATRMEN1KMT2APRKCIGAA | |
| SCHEMBL10094236 | 0.76 | ATR (0.55) | ATRMEN1KMT2ATDP1PRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001042217-A1 | BETA-3 ADRENOCEPTOR AGONISTS | GLAXO GROUP LIMITED (GB) | 2001-06-14 | — | — | WO | disclosed |