Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CNOT7 | Q9UIV1 | 8/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974261 | 0.93 | LMNA (0.60) | KDM4ELMNAPOLBMAPK1CNOT7 | |
| SCHEMBL7985079 | 0.92 | KDM4E (0.49) | KDM4ELMNAPOLBMAPK1CNOT7 | |
| SCHEMBL7975251 | 0.88 | SMN1; SMN2 (0.60) | CNOT7ALDH1A1HPGDSMN1; SMN2KMT2A | |
| SCHEMBL7984707 | 0.87 | CNOT7 (0.48) | KDM4ELMNAPOLBMAPK1CNOT7 | |
| SCHEMBL7988942 | 0.87 | CNOT7 (0.47) | KDM4ELMNAPOLBMAPK1CNOT7 | |
| Hydrochloric Acid SCHEMBL7984347 | 0.86 | CNOT7 (0.47) | KDM4ELMNAPOLBMAPK1CNOT7 | |
| SCHEMBL7987233 | 0.85 | LMNA (0.58) | KDM4ELMNAPOLBMAPK1CNOT7 | |
| SCHEMBL7985770 | 0.83 | CNOT7 (0.50) | LMNAPOLBMAPK1CNOT7ALDH1A1 | |
| SCHEMBL27746499 | 0.82 | PNP (0.55) | KDM4ELMNAPOLBMAPK1CNOT7 | |
| SCHEMBL7985534 | 0.82 | L3MBTL1 (0.44) | KDM4ELMNAPOLBMAPK1CNOT7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |