Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9004078 | 0.86 | SPR (0.40) | SPRALDH1A1GAACYP1A2CYP2C19 | |
| SCHEMBL9004024 | 0.82 | SPR (0.41) | SPRALDH1A1LMNA | |
| SCHEMBL6772639 | 0.80 | SPR (0.40) | SPR | |
| SCHEMBL988443 | 0.77 | SPR (0.40) | SPR | |
| SCHEMBL9004086 | 0.76 | SPR (0.37) | SPRHIF1AKDM4EALDH1A1 | |
| SCHEMBL7833058 | 0.76 | ALDH1A1 (0.41) | SPRKDM4EALDH1A1GAAKMT2A | |
| SCHEMBL1963019 | 0.74 | SPR (0.38) | SPR | |
| SCHEMBL9004056 | 0.73 | SPR (0.35) | SPR | |
| SCHEMBL6768806 | 0.72 | SPR (0.48) | SPR | |
| SCHEMBL8427416 | 0.71 | SPR (0.37) | SPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6297196-B1 | HETEROCYCLIC COMPOUNDS WITH KETONE GROUPS AND OXIMES, PHOSPHONATES OR PHOSPHATES | HOECHST SCHERING AGREVO GMBH (DE) | 2001-10-02 | — | — | US | claimed |
| US-6297196-B1 | HETEROCYCLIC COMPOUNDS WITH KETONE GROUPS AND OXIMES, PHOSPHONATES OR PHOSPHATES | HOECHST SCHERING AGREVO GMBH (DE) | 2001-10-02 | — | — | US | disclosed |