Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.53 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984835 | 0.90 | HCRTR1 (0.60) | HCRTR1MAPTMAPK1GAAMEN1 | |
| SCHEMBL7983685 | 0.88 | HCRTR1 (0.65) | HCRTR1MAPTMAPK1GAAMEN1 | |
| SCHEMBL7983551 | 0.87 | ALDH1A1 (0.56) | HCRTR1MAPTMAPK1MEN1KMT2A | |
| SCHEMBL7973351 | 0.86 | CTSD (0.63) | MAPTMAPK1GAAHSD17B10ALDH1A1 | |
| SCHEMBL7959716 | 0.80 | HCRTR1 (0.73) | HCRTR1MAPTMAPK1GAAMEN1 | |
| SCHEMBL2358299 | 0.80 | HCRTR1 (0.73) | HCRTR1MAPTMAPK1GAAMEN1 | |
| SCHEMBL6400854 | 0.80 | HCRTR1 (0.73) | HCRTR1MAPTMAPK1GAAMEN1 | |
| SCHEMBL29763776 | 0.80 | HCRTR1 (0.73) | HCRTR1MAPTMAPK1GAAMEN1 | |
| SCHEMBL11763044 | 0.79 | HCRTR1 (0.66) | HCRTR1MAPTMAPK1GAAMEN1 | |
| SCHEMBL16829424 | 0.79 | HCRTR1 (0.81) | HCRTR1MAPTMAPK1GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6331628-B1 | REACTING A SUBSTITUTED HALOBENZENE WITH POTASSIUM, SODIUM AND/OR ZINC CYANIDE IN THE PRESENCE OF A METALLIC CATALYST | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2001-12-18 | — | — | US | disclosed |