Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | ALPI | P09923 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7933744 | 0.81 | ALDH1A1 (0.38) | ALDH1A1LMNAHPGDPOLBGAA | |
| SCHEMBL7933742 | 0.81 | ALDH1A1 (0.38) | ALDH1A1LMNAHPGDPOLBGAA | |
| SCHEMBL7930247 | 0.77 | POLB (0.36) | ALDH1A1LMNAPOLBGAAKMT2A | |
| SCHEMBL8137674 | 0.77 | TP53 (0.43) | ALDH1A1POLBGAAKMT2ANOTUM | |
| SCHEMBL8138015 | 0.75 | CYP4F2 (0.41) | ALDH1A1MAPTTP53NPSR1HSD17B10 | |
| SCHEMBL7930248 | 0.70 | POLB (0.36) | ALDH1A1LMNAHPGDPOLBGAA | |
| SCHEMBL10411515 | 0.70 | TDP1 (0.48) | ALDH1A1POLBGAAKMT2ATDP1 | |
| SCHEMBL9423037 | 0.70 | KMT2A (0.38) | ALDH1A1POLBGAAKMT2ATDP1 | |
| SCHEMBL10531901 | 0.69 | BAZ2B (0.43) | ALDH1A1LMNAHPGDGAAKMT2A | |
| SCHEMBL6699195 | 0.66 | CYP4F2 (0.44) | ALDH1A1LMNAKMT2ATDP1CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010031865-A1 | Substituted 3-phenyluracils | KLINTZ RALF (DE) | 2001-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010031865-A1 | Substituted 3-phenyluracils | CCR1, CCR6, CCR3 | ALDH1A1 1864/4885LMNA 1409/4885HPGD 3311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.