Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.40 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8138015 | 0.86 | CYP4F2 (0.41) | TP53CYP4F2CYP4A11HTTALDH1A1 | |
| SCHEMBL6699195 | 0.77 | CYP4F2 (0.44) | CYP4F2CYP4A11HTTALDH1A1KDM4E | |
| SCHEMBL8129422 | 0.77 | NOTUM (0.39) | TP53CYP4F2CYP4A11ALDH1A1KDM4E | |
| SCHEMBL7974768 | 0.77 | ALDH1A1 (0.38) | TP53ALDH1A1KDM4ETSHRSMN1; SMN2 | |
| SCHEMBL7901370 | 0.75 | CYP4F2 (0.39) | TP53CYP4F2CYP4A11HTTALDH1A1 | |
| SCHEMBL10531901 | 0.74 | BAZ2B (0.43) | TP53CYP4F2CYP4A11ALDH1A1KDM4E | |
| SCHEMBL10644841 | 0.73 | SMN1; SMN2 (0.54) | CYP4F2CYP4A11HTTALDH1A1KDM4E | |
| SCHEMBL9706684 | 0.73 | MAPK1 (0.48) | TP53CYP4F2CYP4A11HTTALDH1A1 | |
| SCHEMBL10410041 | 0.73 | MEN1 (0.40) | TP53HTTALDH1A1MAPK1TSHR | |
| SCHEMBL10411515 | 0.72 | TDP1 (0.48) | ALDH1A1KDM4EKMT2APOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6165942-A | Heterocycle-fused pyrimidinone derivative and herbicidal composition | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2000-12-26 | — | — | US | disclosed |
| EP-0970958-A1 | HETEROCYCLE-FUSED PYRIMIDINONE DERIVATIVES AND HERBICIDES | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 2000-01-12 | — | — | EP | disclosed |