Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL290398 | 0.78 | — | — | |
| SCHEMBL19261728 | 0.77 | ALDH1A1 (0.42) | ALDH1A1TSHRALOX15HSD17B10MAPK1 | |
| SCHEMBL1127575 | 0.77 | ALOX15 (0.62) | ALDH1A1TSHRALOX15HSD17B10MAPK1 | |
| SCHEMBL2492204 | 0.75 | ALDH1A1 (0.40) | ALDH1A1TSHRALOX15HSD17B10MAPK1 | |
| SCHEMBL5445279 | 0.71 | ALDH1A1 (0.42) | ALDH1A1TSHRALOX15HSD17B10MAPK1 | |
| SCHEMBL18016418 | 0.69 | — | — | |
| SCHEMBL23829724 | 0.67 | — | — | |
| SCHEMBL8832223 | 0.67 | ALDH1A1 (0.43) | ALDH1A1TSHRALOX15HSD17B10LMNA | |
| SCHEMBL20586584 | 0.67 | ALDH1A1 (0.48) | ALDH1A1TSHRALOX15HSD17B10MAPK1 | |
| SCHEMBL415833 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6280760-B1 | IMPLANTS HAVING MADE-TO-MEASURE COATING WITH SYNTHESIZED CELL-OR TISSUE-SELECTIVE PEPTIDES WHICH IN VITRO STIMULATE ADHESION OF MAINLY THOSE CELL SPECIES WHICH IN EACH CASE ARE INTENDED TO ACCOMPLISH TISSUE INTEGRATION OF APPROPRIATE BIOMATERIAL | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2001-08-28 | — | — | US | disclosed |