Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 8/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | AKT2 | P31751 | 1/20 | 0.37 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | FAP | Q12884 | 2/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10411479 | 0.82 | ALPI (0.49) | CYP1A2HDAC8DPP4FAPDPP8 | |
| SCHEMBL11445439 | 0.73 | NPC1 (0.47) | AKT1AKT2AKT3HDAC8HDAC3 | |
| SCHEMBL2153542 | 0.70 | PKM (0.47) | SLC6A2SLC6A4SLC6A3AKT1AKT2 | |
| SCHEMBL43976 | 0.70 | PKM (0.58) | CYP2C9CYP2C19PPARGPPARA | |
| SCHEMBL43977 | 0.70 | PKM (0.58) | CYP2C9CYP2C19PPARGPPARA | |
| SCHEMBL35491891 | 0.70 | PKM (0.58) | CYP2C9CYP2C19PPARGPPARA | |
| SCHEMBL298903 | 0.70 | PKM (0.58) | CYP2C9CYP2C19PPARGPPARA | |
| SCHEMBL2153547 | 0.70 | PKM (0.47) | SLC6A2SLC6A4SLC6A3AKT1AKT2 | |
| SCHEMBL29351556 | 0.70 | PKM (0.58) | CYP2C9CYP2C19PPARGPPARA | |
| Hydrochloric Acid SCHEMBL1514957 | 0.69 | PKM (0.56) | CYP2C9CYP2C19HDAC8PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277877-B1 | GLYCOGEN PHOSPHORYLASE INHIBITOR; ANTIDIABETIC AGENTS | PFIZER, INC. | 2001-08-21 | — | — | US | disclosed |