Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PKLR | P30613 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985463 | 0.88 | HPGD (0.52) | CACNA1GCACNA1BCACNA1CHPGDALDH1A1 | |
| SCHEMBL7974303 | 0.86 | HPGD (0.42) | CACNA1GCACNA1BCACNA1CHPGDLMNA | |
| SCHEMBL7975225 | 0.86 | CACNA1G (0.40) | CACNA1GCACNA1BCACNA1CLMNATP53 | |
| SCHEMBL7987946 | 0.84 | HPGD (0.42) | CACNA1GCACNA1BCACNA1CHPGDLMNA | |
| SCHEMBL7992290 | 0.83 | HPGD (0.42) | CACNA1GCACNA1BCACNA1CHPGDLMNA | |
| SCHEMBL7991611 | 0.83 | HPGD (0.42) | CACNA1GCACNA1BCACNA1CHPGDLMNA | |
| SCHEMBL7975222 | 0.82 | MCL1 (0.39) | LMNATP53POLBALDH1A1MCL1 | |
| SCHEMBL7988125 | 0.82 | HPGD (0.43) | CACNA1GCACNA1BCACNA1CHPGDALDH1A1 | |
| SCHEMBL7985320 | 0.81 | LMNA (0.47) | CACNA1GCACNA1BCACNA1CHPGDLMNA | |
| SCHEMBL7988933 | 0.81 | GAA (0.44) | CACNA1GCACNA1BCACNA1CHPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |