Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 4/20 | 0.50 |
| ▸ | PPARD | Q03181 | 2/20 | 0.50 |
| ▸ | HTR2C | P28335 | 3/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.45 |
| ▸ | PDE2A | O00408 | 1/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.44 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7978455 | 0.82 | TP53 (0.51) | LMNA | |
| SCHEMBL13210526 | 0.75 | HDAC8 (0.44) | LMNA | |
| SCHEMBL20477542 | 0.75 | EPHX2 (0.74) | EPHX2NR1H4PPARAHTR2CPPARG | |
| SCHEMBL14162989 | 0.74 | CETP (0.61) | TRPV1MAPK14 | |
| SCHEMBL20477564 | 0.74 | HDAC1 (0.59) | EPHX2NR1H4PPARAPPARDHTR2C | |
| SCHEMBL13524538 | 0.72 | LTA4H (0.53) | EPHX2PPARAPPARDPPARGLMNA | |
| SCHEMBL27859550 | 0.72 | EPHX2 (0.62) | EPHX2NR1H4PPARAPPARDHTR2C | |
| SCHEMBL27931800 | 0.72 | EPHX2 (0.70) | EPHX2NR1H4PPARAHTR2CPPARG | |
| SCHEMBL6635990 | 0.72 | EPHX2 (0.61) | EPHX2NR1H4PPARAPPARDHTR2C | |
| SCHEMBL3577590 | 0.71 | EPHX2 (0.73) | EPHX2NR1H4PPARAHTR2CPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001064644-A1 | DICHLOROPYRIDYL- AND DICHLOROISOTHIAZOLYL-THIOCARBOXAMIDES AND THEIR USE AS MICROBICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 2001-09-07 | — | — | WO | disclosed |