SCHEMBL7978455

SCHEMBL7978455

O=C(NCc1ccc(F)cc1)c1snc(Cl)c1Cl

nearest known ligand 0.51

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.50
POLB P06746 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
THRB P10828 1/20 0.46
MAPT P10636 2/20 0.46
KMT2A Q03164 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2C19 P33261 1/20 0.46
MAOB P27338 1/20 0.45
SENP1 Q9P0U3 1/20 0.45
RAB9A P51151 1/20 0.45
LMNA P02545 1/20 0.45
MEN1 O00255 1/20 0.44
ALDH1A1 P00352 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7975262 0.82 EPHX2 (0.52) LMNA
SCHEMBL13210526 0.81 HDAC8 (0.44) TP53L3MBTL1SMN1; SMN2MAPTKMT2A
SCHEMBL6258392 0.81 TP53 (0.51) TP53L3MBTL1POLBSMN1; SMN2THRB
SCHEMBL28544094 0.76 SENP1 (0.45) KMT2AMAOBSENP1MEN1
SCHEMBL6355297 0.74 KMT2A (0.52) TP53L3MBTL1POLBMAPTKMT2A
SCHEMBL7084526 0.74 ALDH1A1 (0.34) SMN1; SMN2ALDH1A1
SCHEMBL7875786 0.73 HPGD (0.59) TP53POLBSMN1; SMN2MAPTKMT2A
SCHEMBL6259715 0.73 FAAH (0.47) TP53L3MBTL1POLBSMN1; SMN2THRB
SCHEMBL3566444 0.72 LMNA (0.42) L3MBTL1SMN1; SMN2MAPTCYP2C19RAB9A
SCHEMBL11536219 0.72 CXCR4 (0.64) L3MBTL1POLBSMN1; SMN2THRBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001064644-A1 DICHLOROPYRIDYL- AND DICHLOROISOTHIAZOLYL-THIOCARBOXAMIDES AND THEIR USE AS MICROBICIDES NIHON BAYER AGROCHEM K.K. (JP) 2001-09-07 WO disclosed